If people with herpes take valacyclovir every day, they can reduce the risk of transmitting herpes to others. Genital Herpes vs Cold Sores There are at least nine viruses in the Herpes family that cause infection in humans. Recently, Human Herpes Virus types 8 and 9 have been identified. Herpes can be a serious health issue for certain people in rare cases. Many people infected with herpes have no symptoms.